I work as a consultant for Lexus, for ALL bluetooth/technology/nav issues. and i can tell you that i took over what Handsfeesolutions used to do for Lexus Santa Monica. Anyway...
1) Look into the Raytel 4000 and find an installer for it, works VERY well. its very very nice and ive used it first hand. best part...$600 installed at some places..look around..
2) No you cant rig the 06 nav to work in your car. if u really want nav, build a car computer and mount the screen where the stock screen went, www.mp3car.com or install the pioneer aftermarket navi there, some dealers will do it for less than/around $2000..
HTH
Abe
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the most stock look would be the es330 navigation unit mounted in place of the 6 disc radio. the price would be 1700.00 and would include the rear view camera moiunted at licence plate lite level and a ntsc dvd movie port. would only need hookups to reverse sensor for camera and the speed sensor. the factrory nav would be a difficult install but possible. i have one of those also but have never tried installing one. the es330 nav CAN BE INSTALLED IN ANY LEXUS.
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The 06MY navigation will not integrate with your 05MY IS300. As another member mentioned an aftermarket unit from Alpine, Eclipse, Kenwood or Pioneer can easily be installed in place of your factory radio. Several aftermarket kits and harnesses make it easy to integrate it with your vehicle. If you really want the same look, and i do mean 'the same', check out Eclipse and Kenwood. You will find that they look identical to the factory system. Plus with the aftermarket stuff you get better equaliziation and you can add a rear camera!
Lastly the comment regarding adding an ES330 navigation is a bit misleading. To do so you would need to get the matching amplifier, cables and so on; much more complicated than it appears to be. I would STRONGLY suggest not taking this route.