I can only say this:
a couple years ago I bought a Jetta (VR6 5 speed, natch). Once in it, I noticed--for the entire time I had it, about 6-9 months--that every Jetta on the road seemed to be driven by a woman. It sure seemed I was the only man in a Jetta.
I kept screaming to myself, IT'S A CHICK CAR!
(This didn't diminish the car in any way for me; no, German engineering and lack of attention to detail did that just fine, thank you very much. I dumped the Jetta for an Accord, and never looked back. But then, I'm a Honda guy from way, way back...but I digress...)
Fast forward to December 25 last year, when the ES300 found its way into my driveway with a big red bow on it. After getting the transmission rebuilt (SURPRISE! I think maybe Toyota has a weak spot in the trannies, but who's going to argue at 125K miles), I've driven the ES exclusively--and have never, ever, ever noticed the "chick car" thing.
So I'm sensitive to it, very aware of the concept from my Jetta days, and the ES simply does not stand out as such in any way.