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For reference, I contacted Sewell Lexus in Dallas. To create new keys from scratch, the car has to be physically present. Proof of ownership is obviously required. If the dealership has the necessary equipment (not all do), they would clear and re-flash the ECU (brain). That essentially removes all knowledge of any prior keys from the car, then they program-in the new key(s). Total cost was quoted at $500 with a new key. Sewell Dallas is typically reasonable, but not all dealerships are. Being in Wisconsin, towing the car to Dallas isn’t feasible, so I suggest calling the Lexus dealers in your area one-by-one and ask if they are able to reflash the ECU and create a new key for you, and at what cost. There may also be independent repair shops that focus on Lexus, so they may be an option as well IF they have the necessary re-flashing equipment. Note that I’m not an expert, so hopefully I described the process appropriately. Good luck.