Mine had some rattle on the first year, as I drive a lot on gravel roads and Off-road. Some patch were put in it the rails but it began to rattle again. I tried to track this problems at Lexus and Toyota on this, but I did not find it. On the second year the moonroof it ratteled more and this time it was taken out fixed and put back in. No problem since then. Now I can drive on 60Mph on a gravel road and no rattle sound in the SUV, that handles super.....
It seems that this is rare problem and it has been the only problem.