As you say, everyone is different, but on our 04 RX330 (currently with 98,000 miles), we wouldn't have used it.
The only problem we have had is warped rotors every 25-28K. I am hoping to have them fixed for good this time around.
The rest of the car has been rock solid.
A few TSBs to have checked out ...
1) Make sure the headlights are sealed -- there have been reports of condensation and they have revised the TSB
2) Get the A/C "moan/whine" fixed under warranty -- It is 2.7 hours for labor, so it will be a bit costly to fix after the fact.
3) You may notice a dash rattle
4) The rear camera (if equipped) has an extended warranty on it ... it is TSB 0702.
What is the fix for the dash Rattle please. It is very anoying.