I got to play with one at the recent auto show here, and yes, I am assured it has full functionality when moving (didn't get to drive it, so I'm merely relaying information). Downside (if there is one) is that Lexus gave up the touch screen, which would be problematic anyway since the screen is deeply recessed; a plus is that there is absolutely no glare, voice-activation really works with "natural" commands (and it is in the RX), and the controls, as reviewed, are completely intuitive and a breeze to use, a vast improvement over BMW's (previous) i-Drive. Waiting for this technology in the GX....