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Would like to know if i can put 245 45 18 tires on my 07 es350 ul without any problems?? I already have 235 45 18s. Would there be much of a difference in look or handling?? Thanx!!

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Since the original factory tire size was 215/55/17 .... and you already have 235/45/18's installed, the only way to tell would be to mount a 245/45/18 and see if it conflicts with the shock tower and the inner fender well.

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