One thing that I have not seen mentioned in the prevous replies is in regard to certain situations that will cause this type of wear on an LS400, or any other rear-drive Lexus vehicles. These cars run a very large amount of caster, in order to provide good stability at the high speeds that they are capable of. Because suspension geometry is a compromise, this high positive caster causes the tires to sit on the edges of the tread when at high steering angles (turn your wheels all the way in either direction to see this). Therefore, if the car is driven frequently in parking lots or does a lot of u-turns, the inside or outside edges can wear rapidly. This is true even if the alignment is perfect. Michelin Energy MXV4 Plus tires are by far the best at resisting this, and are well worth the money. Good luck.