1999 RX300 with 190K miles here. Lots of highway miles (avg 18.9 mpg). Unfortunately, transmission is being rebuilt as we speak. The first major repair for car - to the tune of $4000+ (Acme Transmission).
I try and keep my cars until they reach 300+K miles. I basically just have oil/filter done frequently (between 6K-10K intervals), brake work and then any major work as needed. Other than the first "Warranty" service appointment I don't bring my cars to the Dealer for the recommended (overly expensive and often unrequired IMHO) "maintenance appoitnments" if the car is running well.
Also currently driving a 1998 Saturn SL2 with 260K miles (manual transmission)...no major engine or drive train work done on that car yet. My previous 1992(?) Saturn SL2 went 365K miles (rings at 234K) and was still running but needing significant work when I donated it.
I had a 1983 RX-7 that I sold in 2007 with 396K miles for $200 (major repairs: manual transmission at 217K; shortblock engine rebuild and body work/repaint at 243K). The best and most fun to drive car I've owned so far (love the rotary engine!).
