This chap is spot on the money. Use syns if you want to pamper your baby, but don't do it for financial reasons unless you really plan to keep your car well over 150,000 miles - probably much much more.
Also...
Since over 50% of Lexus' are leased anyway, this discussion has no bearing on those cars whatsoever. Who in their right mind would make the synthetic investment for a car they plan on turning in in a few years.
Also...
Few folks realize that dino oils have made significant advances in the past 20 years. The dino oil you buy today has a much better formulation than just a few years ago; to such an extent that entirely new wear and service classifications have been created. This small fact is almost entirely overlooked when forums such as these debate the differences.
I get routine oil changes, from routine guys, using routine (yet correct) oil. My cars have no trouble heading well over 100,000 and don't burn more than half a quart between changes. Usually the fenders fall off, or I grow bored of the car, before I get material engine wear. I don't need a better argument for dino oils than that.