That code required me to change the bank 2 sensor 2. The sensor is on the passenger side about the middle of the door on the bottom. The sensor is easy to get to, the clip where it plugs into, is not. You have to take out the passenger seat, lift up the carpet and padding, and it is located near the center console. Lexus wanted $198 for their sensor which is a denso, i found a bosch for $161 and right on the sensor it says made by denso. You can buy the cheaper heated sensors and splice them in so that you don't have to do all that, but I wanted to eliminate as many possible problem areas as I could. I did have to change with the cars end of the wiring was mounted a little, just cut the tape, because the new O2 sensors harness was about 5 inches shorter.
I have not had that code or the misfires come up since. Now I am trying to figure out the intake camshaft postion sensor problem and that one requires some engine parts to be taken off.
Hope this helps.
John