IS350 seems already released in Japan.
And the price is about 4000000 yen to 5000000 yen (IS350 model)
The price change to U.S $$ should be around $$ 35,250 ~~ $$ 44,062 (from yahoo currency)
The price is quite big than i thought.
Check this out your self.
http://lexus.jp/models/is/spec/price.html