Hawkswatch

There’s actually many things that can cause the problem. I’m posting the information below to help out the legions of other RX350 owners looking for a nice concise solution to this irritating problem. 1. Make sure the Main/2nd button, underneath the dash on the passenger side, is set to Main (this is the “out” position of this push button.) This can easily get accidentally pushed in by a passenger’s leg. If you are wondering what this switch does, it’s for people that have two sets of tires with pressure sensors on both sets. This might be for a set of snow tires, for example. 2. Inflate all tires to at least 33psi. 3. Make sure you inflate the spare tire too. 4. Make sure you have aluminum valve stem caps on all tires including the spare. Don’t use plastic or non-aluminum metal caps. Other metals can actually fuse to the stems over time! You can probably get them at the dealer, or buy some colored ones on Amazon. 5. Press the TPMS reset button underneath the dash on the driver side. There are two buttons near each other - it’s the one on the left. Well, I hope this information helps someone. The Main/2nd switch is what trips up most people and it wasn’t mentioned on most of the forum posts I've read.