I have a 2001 Lexus RX300 whith 115,000 miles. Out of no where, last week it completely dies on me. Come to find out (after having it towed), the transmission is completely shot. The mechanic said this is not at all the first time he has seen this issue with this make and model. I am in the process of trying to get in touch with Lexus regarding my options. After researching this it appears this has been a MAJOR issue that Lexus needs to deal with. I was in rush hour traffice in Houston, TX and I'm just glad my children were not in the car. This needs to be addressed and I'm on boeard with any action with Lexus.