Landar, thanks for your post. I just went out again and drove the car for maybe six miles. I went though a series of what I considered "Transmission isolation" checks (My term). During normal take off and driving the car does the same thing right around 45 MPH then significantly reduces the vibration as speed increases above 48-50 MPH. I used the term "significantly" because the vibration can still be felt but very lightly or may be un-noticeable to a non-mechanically minded person. I stopped and rapidly accelerated up to 65 MPH and the car drove as new. I repeated this same procedure with the ECM switch on and it drove as it is supposed to. During various driving conditions I turned on/0ff the O/D and the tranny responded on as it should. What I did noticed is that as the car decelerates and reaches within the 45 MPH zone, the vibration starts but the RPM needle is dead steady with absolutely no erratic reading and the engine does not struggle one bit. However, the gear shifter is like an unbalanced washing machine.
To answer your other questions, I last did a full tune up on this car maybe a year ago. Plugs, wires, caps, rotors, etc was changed but the car drove maybe 1500 miles since then. Tranny oil change is approaching four years with less than 5000 miles since it was changed. The car was parked for almost a year without being driven 100 miles. I cleaned the intake, TPS, MAP, inspected filters, hoses, etc and everything seem to be in good shape. This vibration only occurs at a certain RPM/MPH which leads me to think it is related to a dynamic component either out of balance or unsecured. When I get a chance I will inspect the transmission and drive train for obvious issues that could cause this. I'm thinking tranny and/or drive shaft mount is bad since these parts are still original and has been in the ice/heat since birth. I'm also ready to give her up for adoption to a new family in the MD State.