Your IS engine isn't the same as a supra engine, so no you can't just throw a manifold and turbo from a supra on your IS. The supra manifold won't even bolt up on your IS. You can swap your GE with a GTE and have a boosted car but you will need to do a lot of research.
Boost For Is300
in 01 - 06 Lexus IS300
Posted
Your IS engine isn't the same as a supra engine, so no you can't just throw a manifold and turbo from a supra on your IS. The supra manifold won't even bolt up on your IS. You can swap your GE with a GTE and have a boosted car but you will need to do a lot of research.