Simple. I am a Toyota fan ever since my dad had the 87 Camry and 88 MR2 (after owning a dreaded unreliable Ford Mustang) and my dream was to own the elite Toyota brand. Today, I own a 91 MR2 and an 04 RX330 and am exceptionally pleased with both. They both have similar mileage, around 120 000 km and have both been exceptionally reliable. Actually, the MR2 even more so (very few electronics as the possible reason). Considering our Canadian Winters and past ownership of a Toyota RAV4 and Honda CRV, an SUV/4WD vehicle was a no-brainer. Factor in growing kids and extra cargo/interior room that comes along with that, the RX330 was a no-brainer, especially when it's only 4-5G$ Cnd more than an American "lesser" model (Jeep Grand Cherokee Limited, Ford Explorer Eddie Bauer, etc.)
Finally, the Americans (and to a lesser degree, the Germans) still don't have the refinement, build quality, and reliability the Japanese have in their vehicles. Would you want to coddle yourself in a cabin straight out of a Chevy/GMC full-size pickup with splashes of tacked on (literally) Zebrano wood in the pre-2007 Cadillac Escalade for $$ more than the RX or even a GX? Unless of course you wait for the 10G$ GM rebates and 0% financing that happens every other month. Even for 10$G cheaper, I wouldn't want it... to stare at a cheap-plastic looking, straight lined and grey-buttoned GM Delco radio found in my uncle's 92 Lumina... the DASH BOARD is straight out of the seventies... Even the steering wheel column and key ignition with its "flaps" (remember those in your father's Oldsmobile where you put the key in and turn the entire flap/key combo to start the car) dates back to prehistoric times. Sad and embarrassing for the 21st century, especially for $70 G Cnd.
To their defence, the 2007 Escalade is vastly improved, surpassing the Lincoln Navigator, but still only 80% a Lexus SUV is.
Off topic: Yes, go for the IS (350)... smallish, but incredibly refined and powerful!