Yea. PIONEERSUBY, a member on this forum, can change the factory changer to work with the newer IP-Bus interface. Unfortunately, it costs $50 to get it done. Since I use my iPod the majority of the time, it's hard to justify the cost.
Here's the link: http://us.lexusownersclub.com/forums/index...showtopic=30845
Pretty soon, I think I'm going to take out the changer and put a PS2 in it's place