My '92 ES300 just rolled over 250K today(!). It runs great.
(Note: I don't usually cruise at redline. This was a special occasion!)
And here's the video:
Video of 1992 ES rolling over 250K
I'm sure there are ES300's out there with 300K+. In the last few years mine has gradually increased it's oil consumption to the tune of 1 qt/2000 miles. I believe this is mostly due to oil leakage through the valves as it cools down, which creates a puff of blue smoke at almost every cold start. There is _no_ sign of oil coming out the exhaust when running warm.
Apart from wear-and-tear items I consider part of routine maintenance (CVs, timing belt, struts, brakes), the only mechanical parts it has needed are: valve cover gaskets, steering rack, and a radiator. Given that it's been driven a steady 18K per year for nearly 14 years, I'm amazed that it's never needed a wheel bearing, a starter, an alternator, any pump or other mechanical accessory. Apart from the blinking instrument cluster needles, the only electronic failures have been a power window switch panel and the CD player (it kept ejecting the magazine).
I'd like to keep driving it until the oil consumption gets unreasonable and/or engine failure, at which point someone should swap in a good used powerplant - because the body is currently excellent, and the rest will doubtlessly still function. I doubt I'll have the interest in renewing it's life, since the form factor is becoming less and less of a fit with our family lifestyle. Rather a pity.
But it has been, and continues to be, economical, comfortable, reliable luxury. It looks and drives like it's fuel comes from the fountain of youth!