Yep, my former RX300 had the transmission fail at exactly 101k miles, the fluid had been changed prior. I have heard of many Honda's etc having transmission failures. My thoughts on the fluid change is that it is cheap insurance to provide fresh fluid with no breakdown. Yes these cars have coolers, but that doesn't mean that gears, bands, plates etc aren't going to contaminate the fluid. I changed the fluid on My Present RX400h at 80k miles and the fluid was brown. That is not a good color for any transmission fluid. Lifetime, and I mean this is strictly a sales gimmick to make consumers feel there is no additional cost of maintenance. I am on five car forums and I can guarantee the consensus is change the fluid. Note: I have been tracking transmission failures for years on the Lexus RX300 and I have emails from no less than 100 people with this problem. All said the same thing, (I thought Lexus/Toyota products were a reliable product) All cars have failures, but preventative is the best medicine.